Medicines in the fridge

2018-05-16 17:09:39

Why are there some medicines that are put in the fridge?

Thanks

Chemical reactions are slowed down at lower temperatures; refrigeration can increase the shelf-life of medicines that would not last long enough at room temperature.

Refrigeration could be important for the active ingredient or for the formulation as a whole.

Note that refrigeration can also be a problem for some formulations, so it's important to follow storage instructions.

The effects of short-term failure to refrigerate drugs that are supposed to be refrigerated varies, see Cohen et al. 2007 for a compilation of manufacturer instructions for a variety of drugs.

References

Cohen, V., Jellinek, S. P., Teperikidis, L., Berkovits, E., & Goldman, W. M. (2007). Room-temperature storage of medications labeled for refrigeration. American Journal of Health-System Pharmacy, 64(16), 1711-1715.

  • Chemical reactions are slowed down at lower temperatures; refrigeration can increase the shelf-life of medicines that would not last long enough at room temperature.

    Refrigeration could be important for the active ingredient or for the formulation as a whole.

    Note that refrigeration can also be a problem for some formulations, so it's important to follow storage instructions.

    The effects of short-term failure to refrigerate drugs that are supposed to be refrigerated varies, see Cohen et al. 2007 for a compilation of manufacturer instructions for a variety of drugs.

    References

    Cohen, V., Jellinek, S. P., Teperikidis, L., Berkovits, E., & Goldman, W. M. (2007). Room-temperature storage of medications labeled for refrigeration. American Journal of Health-System Pharmacy, 64(16), 1711-1715.

    2018-05-16 18:57:19